Promotion of spinosad biosynthesis by chromosomal integration of the Vitreoscilla hemoglobin gene in Saccharopolyspora spinosa
نویسندگان
چکیده
منابع مشابه
A New Medium for Improving Spinosad Production by Saccharopolyspora spinosa
BACKGROUND Spinosad (a mixture of spinosyns A and D) is a unique natural pesticide produced by Saccharopolyspora spinosa. With regard to attempts to improve S. spinosa by classical mutagenesis, we propose that the bottleneck of screening out high-spinosad-production strains is probably caused by the fermentation media. OBJECTIVES The current study aimed to identify a new medium to extensively...
متن کاملstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
a new medium for improving spinosad production by saccharopolyspora spinosa
materials and methods statistical and regressive modeling methods were used to investigate the effects of the carbon source and to optimize the production media. results the spinosad production of s. spinosa co121 increased 77.13%, from 310.44 ± 21.84 μg/ml in the initial fermentation medium (with glucose as the main carbon source) to 549.89 ± 38.59 μg/ml in a new optimized fermentation medium ...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولGenome-scale metabolic network reconstruction of Saccharopolyspora spinosa for Spinosad Production improvement
BACKGROUND Spinosad is a macrolide antibiotic produced by Saccharopolyspora spinosa with aerobic fermentation. However, the wild strain has a low productivity. In this article, a computational guided engineering approach was adopted in order to improve the yield of spinosad in S. spinosa. RESULTS Firstly, a genome-scale metabolic network reconstruction (GSMR) for S.spinosa based on its genome...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science China Life Sciences
سال: 2012
ISSN: 1674-7305,1869-1889
DOI: 10.1007/s11427-012-4276-0